About us


dynamic bio-medical start-up, the team full of crazy ideas. We combine the power of chemistry and biology in the fight against cancer!

Our team


Marek BorzestowskiSerial entrepreneur; previously Founder, Chairman and CEO of one of Poland’s leading internet portals, Wirtualna Polska. Former Director & Co-Owner of Centrum Nowych Technologii (Centre for New Technologies). He has been active in the field of nanotechology since the 1990s, and is Chairman of the listed bioscience company NanoGroup SA. Mr. Borzestowski has a Master of Business and Management degree from Swansea University and a master’s degree in Business and Managerial Economics from Gdansk Polytechnic.
Tomasz CiachSpecialist in nanotechnology with extensive academic and business experience. Head of biotechnology and bioprocess engineering at the Warsaw Technical University. 12 granted patents, 2 technologies in production. He is founder of 4 companies and a consultant to AstraZeneca, Procter and Gamble, Reckit, Adamed, Balton, Galmed. Prof. Ciach holds an MA in Biology from the University of Warsaw and a PhD in Chemical Engineering from the Warsaw University of Technology.
Izabela GałązkaHighly experience financial executive, formerly with private and listed companies in banking, insurance, real estate and advisory/consulting. Responsible for reporting to the Polish Financial Supervision Authority (KNF), the Central Securities Depository of Poland (KDPW), and the Warsaw Stock Exchange. Ms. Gałązka has completed a Masters of Economics degree from Gdansk University and Post-Graduate studies in Banking and Finance at Gdansk University jointly with London Guildhall University.


Adam KiciakGeneral surgeon, specialized in colorectal and bariatric surgery, as well as phlebology. Previously medical advisor in Pfizer Inc. Former Vice-President for R&D in Biolek Ltd (Bioton SA Group). Co-inventor of patent P. 381 603 and co-author of a product widely used in gastroenterology. Within NanoGroup responsible for preclinical and clinical studies coordination. Dr. Kiciak has MD and PhD degrees from Warsaw Medical University.
Wioletta KośnikA graduate of the University of Warsaw. Doctor of the Institute of Organic Chemistry of the Polish Academy of Sciences. Experienced chemist in the field of organic synthesis and analysis of organic compounds. She got acquainted with pharmaceutical production while working at Adamed Pharma S.A. She conducted research under numerous research grants (including the prestigious TEAM program), which resulted in over 15 scientific publications in renowned journals and 2 European patent applications. A graduate of research internships and trainings – including Postgraduate Studies in Project Management, conducted by the Warsaw School of Economics. Skills confirmed by the PRINCE2® certificate. Climbing enthusiast.
Anna RedwanExpert in external funding and implementation of new technologies – in 2005-2021, manager of high-budget projects with EU funding. A graduate of the Faculty of Law at the University of Warsaw, a graduate of Postgraduate Management Studies in Project Management at the Management Faculty of the University of Warsaw, a graduate of Postgraduate Studies in New Marketing (Social Media), Collegium da Vinci, graduate of the Stock Exchange School of the WSE Main Market. As a hobby and profession, also Project/Event and Social Media Manager, organizer and coordinator of cultural, educational and scientific events.


Wioletta Kośnik
Paweł Żuk
Joanna Pietras


Anna Potyńska
Paweł Ciach
Piotr Pietrzak

Our development path

  Drug Delivery Systems  

Our dextran drug delivery system was first developed at the Faculty of Chemical and Process Engineering of the Warsaw University of Technology in the Biomedical Engineering Laboratory established by Dr. Tomasz Ciach. In 2013 GIZA Polish Ventures, together with Dr. Ciach decided to commercialize the technology and founded NanoVelos. Since then we work hard to broaden our portfolio of dextran-drug conjugates. In parallel, we explore new areas of interest eg. drug formulation development for lubrication of joints or sinusitis treatment.

  Drug Delivery Systems  
Our nanoparticles

are produced from various polysaccharides (e.g. from oxidized Dextran) without use of toxic substances or metal particles. Dextran can form a nanoparticles backbone composed of 10 modified dextran subunits, stabilized by the addition of coiling agents. Nanoparticles can serve as drug carriers with a pH-dependent drug bond that allows release of the drug solely within cancer cells. Technology based on polysaccharide nanoparticles is orginal solution patented by NanoVelos SA In vitro experiments: Assesment of cell viability (MTT assay, HeLa cells etc.) demonstrates that examined drugs released from nanoparticles retains its potential to induce cell death.

  Drug Delivery Systems  
Preclinical studies

Non-clinical studies form the basis for further clinical studies and drug development in humans. Usually this part consists of in-vitro (cell culture) and in-vivo (animals) studies of a new drug substance or drug carriers. The main goals of those studies is to collect the data providing submission to FDA or EMA. Preclinical studies as a first step of drug development process include: screening tests; tests on cell cultures; pharmacokinetics (single and multiple dose) and toxicity (MTD test) on healthy animals (mouse, rats, guinea pig); efficacy tests on animal models of human diseases.

Preclinical studies must meet with EMA and FDA requirements and be done under GLP (Good Laboratory Practice) rules. GLP refers to a quality system of laboratories and ensure uniformity, consistency, quality and integrity of non-clinical studies starting from physicochemical analysis through the animal trials.

The pharmacokinetics, toxicity and efficacy tests of dextran nanoparticles containing various drugs have been comprehensive studied.

Our results indicate that several of our nanoparticles induced an important cytotoxicity in vitro, but showed decreased toxicity in vivo–evidenced and sufficient pharmacokinetics.

  Drug Delivery Systems  
Human clinical studies

Through clinical trials, scientists and doctors determine safety and efficacy of new treatments. There are two main types of clinical studies: clinical trials and observational studies. Clinical trials involve human volunteers that is intended to develop medical knowledge how to prevent and detect cancer cells, how to improve the quality of life for patients during and after therapy. In a clinical trial, participants receive specific interventions according to the research plan or protocol prepared by the investigators. These interventions may be medical products, such as drugs or devices; procedures; or changes to participants’ behavior, such as diet. Clinical trials may compare a new medical approach to a standard one that is already available, to a placebo that contains no active ingredients, or to no intervention. When a new product or approach is being studied, it is not usually known whether it will be helpful, harmful, or no different than available alternatives. The investigators are obliged to determine the safety and efficacy of the intervention by measuring certain outcomes in the participants.

To successfully register new cancer treatments some phases must be done:

Phase 1 and 2: Exploratory study involving very limited human exposure to the drug. Researchers need to establish whether a new treatment is safe, what kind of side effects are, and the best dose of the new treatment. In oncological trials, in phase 1 studies also gather preliminary data on effectiveness for example slowing the tumor growth.

In phase 3: investigators study whether the treatment works better than the current standard therapy, also compare the safety of the new treatment with current one. Phase 3 include larger numbers of participants to make sure that obtained results are reliable.

Generally, in clinical trials is described also very early ‘phase 0’ and later ‘phase 4’. Phase 0 include very small trials to evaluate if a new agent should be tested in a phase 1 trial, whereas phase 4 study a long-term safety and effectiveness. This phase 4 is conducted after a new treatment has been approved and is on the market.

  Drug Delivery Systems  
FDA/EMA Approval

The EMA (European Medicines Agency), is the European Union’s equivalent to the U.S. Food and Drug Administration (FDA). If the EMA grants approval, the drug can be used throughout the European Union and in Iceland, Norway and Liechtenstein, FDA on the territory of the United States. Before new drug goes to market first companies have to run tests in laboratory and on different animals. In the end they bring that data to the EMA/FDA in the form of an Investigational New Drug application. If the EMA/FDA signs documents, the company starts testing the drug on humans. To see if the drug is safe and effective when used to treat or diagnose a disease.

  Drug Delivery Systems  

Everything is in flux: markets, science and competitors change constantly, and a company attempting to bring a drug to market must stay on top of and roll with the dynamic landscape. Defining of our patient population is essential from a regulatory, clinical, payer and commercial perspective. It gives us an opportunity and risk trade-offs, and lends valuable insight to strategic decision-making and scenario planning. Treatments are not one-size-fits-all, that’s why we focus on various areas.


Dextran nanoparticles

  • Dextran nanoparticles can serve as drug carriers (e.g., for doxorubicin) with a pH-dependent drug bond that allows the release of the drug solely within cancer cells.
  • Dextran nanoparticles can be stored in a dry state and easily reassembled in water.
  • Dextran can form a nanoparticle backbone composed of 10 modified dextran subunits, stabilized by the addition of coiling agents.
  • The physical properties of dextran nanoparticles can be modified by changing the synthesis protocol.

Drug Delivery Systems

Drug Delivery Systems


Drug Delivery Systems


Drug Delivery Systems

SEM with Ionic liquid (solvation of nanoparticles)


  Drug Delivery Systems  

Widely proven targeting


Controlled drug release

  Drug Delivery Systems